World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 8, Number 3, June 2017, pages 71-75


A Retrospective Analysis of Clinical Utility of AJCC 8th Edition Cancer Staging System for Breast Cancer

Tables

Table 1. Patients and Tumor Characteristics
 
CharacteristicN%
Age, years
  < 3512115.5%
  ≥ 3566384.5%
Menopausal status
  Postmenopausal9812.5%
  Premenopausal68687.5%
T stage at diagnosis
  T129237.2%
  T243956.0%
  T3354.5%
  T4182.3%
N status at diagnosis
  N038148.6%
  N122328.4%
  N210513.4%
  N3759.6%
M status at diagnosis
  M076497.4%
  M1202.6%
ER status
  Positive59475.8%
  Negative19024.2
PR status
  Positive51365.4%
  Negative21734.6%
HER2 status
  Positive23830.4%
  Negative54669.6%

 

Table 2. Distribution of the Prognostic Stage and TNM Stage of the Patients
 
TNM stagePrognostic stage
IAIBIIAIIBIIIAIIIBIIICIVUnknownTotal
IA1254221000000188 (24.0%)
IIA01392832440000243 (31.0%)
IIB01710252314077157 (20.0%)
IIIA0144591110400102 (13.0%)
IIIB0000034007 (0.9%)
IIIC0000231340067 (8.5%)
IV000000020020 (2.6%)
Total (%)125 (15.9%)212 (27.0%)54 (6.9%)91 (11.6%)82 (10.5%)67 (8.5%)56 (7.1%)20 (2.6%)77 (9.8%)

 

Table 3. Change of TNM Stage and Prognostic Stage
 
TNM stagePrognostic stage
StageNStageN (%)
IA188IA12 (66.5%)
IB42 (22.3%)
IIA21 (11.2%)
IIA243IB13 (57.2%)
IIA28 (11.5%)
IIB32 (13.2%)
IIIA44 (18.1%)
IIB157IB17 (10.8%)
IIA1 (0.6%)
IIIA25 (15.9%)
IIIB23 (14.6%)
IIIC14 (8.9%)
Unknown77 (49.0%)
IIIA102IB14 (13.7%)
IIA4 (3.9%)
IIB59 (57.8%)
IIIA11 (10.7%)
IIIB10 (9.8%)
IIIC4 (3.9%)
IIIB7IIIB3 (42.9%)
IIIC4 (57.1%)
IIIC67IIIA2 (3.0%)
IIIB31 (46.3%)
IIIC34 (50.7%)
IV20IV20 (100%)

 

Table 4. Distribution of Prognostic Stage and Subtype
 
StageLuminal ALuminal B HER2 positiveLuminal B HER2 negativeTriple negativeHER2-enrichedP value
IA37 (42.0%)26 (16.4%)61 (17.1%)01 (1.3%)< 0.001
IB31 (35.2%)65 (40.9%)99 (27.8%)017 (22.1%)
IIA3 (3.4%)1 (0.6%)21 (5.9%)18 (17.3%)11 (14.3%)
IIB6 (6.8%)18 (11.3%)56 (15.7%)011 (14.3%)
IIIA010 (6.3%)10 (2.8%)40 (38.5%)22 (28.6%)
IIIB1 (1.1%)17 (10.7%)29 (8.1%)18 (17.3%)2 (2.6%)
IIIC06 (3.8%)16 (4.5%)24 (23.1%)10 (13.0%)
IV1 (1.1%)3 (1.9%)9 (2.5%)4 (3.8%)3 (3.9%)
Unknown9 (10.2%)13 (8.2%)55 (15.4%)00
Total88 (11.2%)159 (20.3%)356 (45.4%)104 (13.3%)77 (9.8%)