Figure 1. Overall postoperative cancer-specific survival of patients.
| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Original Article
Volume 9, Number 5-6, November 2018, pages 136-140
Serum Carcinoembryonic Antigen Level Predicts Cancer-Specific Outcomes of Resected Non-Small Cell Lung Cancer With Interstitial Pneumonia
Figures
Tables
| Number of patients | |
|---|---|
| %VC: percentage of vital capacity; UIP: usual interstitial pneumonia; CEA: carcinoembryonic antigen; CYFRA21-1: cytokeratin 19 fragments; SCC: squamous cell carcinoma-related antigen; KL-6: Krebs von den Lungen-6. | |
| Age | |
| < 65 | 16 |
| ≥ 65 | 25 |
| Gender | |
| Male | 31 |
| Female | 10 |
| Smoking status | |
| Never | 8 |
| Current/former | 33 |
| %VC | |
| < 80 | 5 |
| ≥ 80 | 36 |
| UIP | |
| UIP | 17 |
| non-UIP | 24 |
| Histology | |
| Adenocarcinoma | 21 |
| Squamous cell carcinoma | 14 |
| Others | 6 |
| Surgical procedure | |
| Lobectomy | 35 |
| Sublobar resection | 6 |
| pStage | |
| I | 30 |
| II - III | 11 |
| pT status | |
| pT1 | 25 |
| pT2-3 | 16 |
| pN status | |
| pN0 | 34 |
| pN1-2 | 7 |
| CEA | |
| Normal | 21 |
| High | 20 |
| CYFRA21-1 | |
| Normal | 24 |
| High | 17 |
| SCC | |
| Normal | 31 |
| High | 10 |
| KL-6 | |
| Normal | 22 |
| High | 19 |
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| Hazard ratio | P value | 95% CI | Hazard ratio | P value | 95% CI | |||
| Lower | Upper | Lower | Upper | |||||
| %VC: percentage of vital capacity; UIP: usual interstitial pneumonia; CEA: carcinoembryonic antigen; CYFRA21-1: cytokeratin 19 fragments; SCC: squamous cell carcinoma-related antigen; KL-6: Krebs von den Lungen-6; CI: confidence interval. | ||||||||
| Age | 0.651 | 0.294 | 0.275 | 1.440 | ||||
| Gender | 0.695 | 0.420 | 0.254 | 1.634 | ||||
| Smoking status | 0.542 | 0.230 | 0.158 | 1.422 | ||||
| %VC | 0.380 | 0.120 | 0.138 | 1.338 | ||||
| UIP pattern | 0.566 | 0.160 | 0.252 | 1.256 | ||||
| Surgical procedure | 0.452 | 0.120 | 0.187 | 1.257 | ||||
| Histology | 0.793 | 0.556 | 0.363 | 1.731 | ||||
| pT status | 0.425 | 0.035 | 0.193 | 0.939 | 0.501 | 0.092 | 0.224 | 1.122 |
| pN status | 0.440 | 0.109 | 0.184 | 1.224 | ||||
| CEA | 0.209 | < 0.001 | 0.083 | 0.483 | 0.223 | 0.001 | 0.087 | 0.524 |
| CYFRA21-1 | 0.488 | 0.079 | 0.222 | 1.088 | ||||
| SCC | 0.453 | 0.084 | 0.199 | 1.120 | ||||
| KL-6 | 0.522 | 0.102 | 0.236 | 1.140 | ||||