World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
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Case Report

Volume 10, Number 3, June 2019, pages 153-156

Acute Myeloid Leukemia Acquiring Promyelocytic Leukemia-Retinoic Acid Receptor Alpha at Relapse


Figure 1.
Figure 1. Bone marrow biopsy showing hypocellular marrow for age (× 100).
Figure 2.
Figure 2. Bone marrow biopsy showing infiltration of marrow by monomorphic cells with fine chromatin and moderate amounts of granular cytoplasm (× 400).
Figure 3.
Figure 3. Bone marrow biopsy. Promyelocyte (blast equivalent) showing Auer rods and cytoplasmic coarse granules and fine chromatin (oil, × 1,000).
Figure 4.
Figure 4. Bone marrow biopsy. Promyelocyte with Auer rod marked with black arrow.
Figure 5.
Figure 5. Flow cytometry. The blasts show high side scatter indicating complex cytoplasm.
Figure 6.
Figure 6. Flow cytometry. The blasts are positive for CD117 and negative for CD34 and HLA-DR, highly suggestive of APL.