World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://www.wjon.org

Original Article

Volume 14, Number 1, February 2023, pages 51-59

Uses of Vascular Endothelial Growth Factor C as a Lung Adenocarcinoma Prognostic Biomarker

Figures

Figure 1.
Figure 1. Overall survival curves of VEGF-C in LUAD from different database (a) Ualcan. (b) GEPIA. (c) OncoLnc. (d) TCGA portal. (e) Results of meta-analysis from LCE. LUAD: lung adenocarcinoma; VEGF-C: vascular endothelial growth factor C.
Figure 2.
Figure 2. (a) VEGF-C mRNA expression in LUAD (Ualcan, P = 7.41 × 10-3). (b) VEGF-C mRNA expression in LUAD (GEPIA, P < 0.05). (c) VEGF-C mRNA expression in LUAD based on stage (GEPIA, P = 0.0241). (d) VEGF-C protein expression in LUAD (Ualcan, P = 0.195). (e) VEGF-C mRNA expression between driver mutated (red) and not-mutated (gray) samples (TCGA portals). LUAD: lung adenocarcinoma; VEGF-C: vascular endothelial growth factor C.
Figure 3.
Figure 3. (a) A composite gene-gene functional interaction network. (b) GO of VEGF-C in LUAD. (c) KEGG pathway of VEGF-C in LUAD. LUAD: lung adenocarcinoma; VEGF-C: vascular endothelial growth factor C.
Figure 4.
Figure 4. Tr1 cells (a) and CD4 T cells (b) were correlated with OS in LUAD. Tr1 cells (c) and CD4 T cells (d) were not correlated with VEGF-C expression in LUAD. LUAD: lung adenocarcinoma; VEGF-C: vascular endothelial growth factor C.
Figure 5.
Figure 5. Correlation between VEGF-C expression and drugs sensitivity from GDSC (a) and CTRP (b). VEGF-C: vascular endothelial growth factor C.