| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website https://www.wjon.org |
Review
Volume 14, Number 5, October 2023, pages 340-349
Biology of Mesothelin and Clinical Implications: A Review of Existing Literature
Table
| Tumor type | Reference | # Positive | mAb used | Total portion positive |
|---|---|---|---|---|
| *Non-mucinous. Totals do not include those stained with 5B2 by Inaguma et al to avoid counting the same patients twice. | ||||
| Epithelioid mesothelioma | Chang [19] | 15/15 | K1 | 150/163 (92.0%) |
| Ordonez [20] | 44/44 | 5B2 | ||
| Weidemann [24] | 16/25 | MSVA-235 | ||
| Inaguma [33] | 73/79 | 5B2 | ||
| Inaguma [33] | 75/79 | MN1 | ||
| Epithelial ovarian cancer* | Chang [19] | 10/15 | K1 | 617/655 (94.2%) |
| Hassan [25] | 34/48 | K1 | ||
| Ordonez [20] | 32/34 | 5B2 | ||
| Weidemann [24] | 497/511 | MSVA-235 | ||
| Inaguma [33] | 42/47 | 5B2 | ||
| Inaguma [33] | 44/47 | MN1 | ||
| Pancreatic adenocarcinoma | Ordonez [20] | 12/14 | 5B2 | 267/298 (89.6%) |
| Hassan [21] | 18/18 | 5B2 | ||
| Argani [22] | 60/60 | 5B2 | ||
| Johnston [26] | 10/10 | 5B2 | ||
| Weidemann [24] | 48/64 | MSVA-235 | ||
| Inaguma [33] | 100/132 | 5B2 | ||
| Inaguma [33] | 119/132 | MN1 | ||
| Gastric adenocarcinoma | Ordonez [20] | 2/7 | 5B2 | 920/1,878 (49.0%) |
| Baba [27] | 124/212 | HBME-1 | ||
| Einama [28] | 49/110 | 5B2 | ||
| Han [29] | 30/117 | Not reported | ||
| Shin [30] | 476/958 | SP74 | ||
| Weidemann [24] | 176/393 | MSVA-235 | ||
| Inaguma [33] | 60/81 | 5B2 | ||
| Inaguma [33] | 63/81 | MN1 | ||
| Triple negative breast cancer | Tchou [23] | 29/43 | 5B2 | 178/449 (39.6%) |
| Bayoglu [31] | 30/71 | SP74 | ||
| Tozbikian [32] | 82/226 | 5B2 | ||
| Parinyanitikul [34] | 37/109 | 5B2 | ||