World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 1, Number 3, June 2010, pages 129-134

Phyllodes Tumors of the Breast: A Review of 26 Cases

Figures

Figure 1.
Figure 1. Mammography revealing a lobulated mass with smooth margins.
Figure 2.
Figure 2. Ultrasound of the breast revealing a solid smooth bordered mass with cystic spaces.
Figure 3.
Figure 3. Benign phyllodes tumor: a well-circumscribed biphasic neoplasm containing leaf-like, epithelial-lined papillary projections penetrating into cystic spaces (HE x 40).
Figure 4.
Figure 4. Borderline PT consisting predominantly of a stromal overgrowth, with some ducts (HE x 400).
Figure 5.
Figure 5. Stromal cells of a malignant PT showing marked nuclear atypia and frequent mitoses (HE x 400).

Table

Table 1. Population Characteristics by PT Grade
 
BenignBorderlineMalignant
*One patient developed recurrent disease at 10 months and lung metastases at 21 months.
Number of patients1376
Mean age (range)35.8 (19 - 55)44.7 (34 - 52)45.2 (29 - 66)
Size
  < 5 cm623
  ≥ 5 cm753
Surgical approach
  breast-conserving surgery1262
  mastectomy114
Surgical margin
  negative644
  close532
  indeterminate200
Outcome
  Recurrence13*2
  Metastases01*2
  Favorable1040
  Lost to follow-up202