| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Original Article
Volume 1, Number 4, August 2010, pages 167-172
Clinical and Pathological Response to Neoadjuvant Anthracycline Based Chemotherapy in women with breast cancer
Tables
| Characteristics | Number of Patients | Percentage | |
|---|---|---|---|
| * TNM classification: ER - estrogen receptor, PR - progesterone receptor, HR - hormonal receptor | |||
| Age (years) | < 50 years | 62 | 56% |
| ≥ 50 years | 47 | 43% | |
| Menopausal status | Pre- | 46 | 42% |
| Post | 63 | 58% | |
| Clinical T stage* | T2 | 6 | 5.5% |
| T3 | 39 | 36% | |
| Clinical node stage* | N0 | 46 | 42% |
| N1 | 39 | 36% | |
| N2 | 24 | 22% | |
| Histology | Invasive ductal carcinoma | 102 | 93% |
| Invasive lobular carcinoma | 6 | 5.5% | |
| Other | 1 | 0.9% | |
| Histological grade | Grade 1 | 20 | 18% |
| Grade 2 | 64 | 59% | |
| Grade 3 | 20 | 18.5% | |
| ER | Positive | 73 | 70% |
| Negative | 32 | 30% | |
| PR | positive | 44 | 42% |
| negative | 61 | 58% | |
| HR | positive | 67 | 70% |
| negative | 29 | 30% | |
| HER2 | 0/+/++ | 58 | 53% |
| +++ | 28 | 26% | |
| Parameters | N° of Patients | N° With cCR (%) | P Value | |
|---|---|---|---|---|
| Histological grade | Grade I, II | 20 | 12 (60%) | 0.9 |
| Grade III | 84 | 53 (63%) | ||
| pCR | No | 100 | 6 (61%) | 0.2 |
| Yes | 8 | 7 (87%) | ||
| ER | Positive | 73 | 45 (61%) | 0.2 |
| Negative | 32 | 19 (84%) | ||
| PR | Positive | 44 | 26 (59%) | 0.3 |
| Negative | 61 | 38 (62%) | ||
| HER2 | 0/+/++ | 58 | 36 (62%) | 0.6 |
| +++ | 28 | 18 (64%) | ||