World J Oncol

World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access

Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc

Journal website http://www.wjon.org

Original Article

Volume 2, Number 1, February 2011, pages 10-15

Expression of HLA-I, CD8, and CD4 and Their Clinical Significance in Cervical Cancer

Figures

Figure 1. Tissue staining of HLA-I in different groups. (A) chronic cervicitis, (B) peri-cancer tissue, (C) carcinoma in situ, (D) cervical cancer. (SP, × 400)

Figure 2. Expression of CD8 in different groups. (A) chronic cervicitis, (B) peri-cancer tissue, (C) CIN, (D) cervical cancer. (SP, × 400)

Figure 3. Expression of CD4 in different groups. (A) chronic cervicitis, (B) peri-cancer tissue, (C) CIN, (D) cervical cancer. (SP, × 400)

Tables

**Table 1.** Expression of HLA-I Antigen, CD8 and CD4 in Cervical Cancer
Index	Case	Expression of HLA-I antigen				Expression of CD8				Expression of CD4
Index	Case	-	+	++	+++	-	+	++	+++	-	+	++	+++
Clinicopathological stage
Stage I	14	8	5	1	0	9	5	0	0	8	5	1	0
Stage = 2 \* ROMAN II	6	4	2	0	0	4	2	0	0	3	1	2	0
Differentiation
High	4	3	1	0	0	3	1	0	0	3	0	1	0
Moderate	9	5	3	1	0	6	3	0	0	5	3	1	0
Low	7	4	3	0	0	4	3	0	0	3	3	1	0
Lymph node metastassis
No	16	11	5	0	0	10	6	0	0	8	5	3	0
Yes	4	3	1	0	0	3	1	0	0	3	1	0	0

**Table 2.** Correlations Between HLA-I and CD8 in Different Groups
		HLA-I
		+	++	+++	-	total
	+	25	2	0	0	27
	++	0	16	2	0	18
CD8	+++	0	0	1	0	1
	-	1	0	0	13	14
	total	26	18	3	13	60