| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Review
Volume 3, Number 3, June 2012, pages 93-96
A Review of Novel Systemic Therapies and Brain Radiosurgery for Metastatic Melanoma
Table
| Treatment | Partial response (decrease in tumor size by at least 50%) | Complete response (no tumor detectable) | Overall Response | Median Overall Survival | Reference |
|---|---|---|---|---|---|
| Biochemotherapy vs. Chemotherapy | 21% vs. 15% | 7% vs. 3.5% | 28% vs. 18.5% | No difference | 2 |
| Interleukin 2 | 10% | 6% | 16% | 11.4 months | 7 |
| Ipilimumab vs. Chemotherapy | 13.6% vs. 9.5% | 1.6% vs. 0.8% | 15.2% vs. 10.3% | 11.2 months vs. 9.1 months | 20 |
| Vemurafenib vs. Chemotherapy | 47% vs. 5% | 1% vs. 0% | 48% vs. 5% | At 6 months: 84% vs. 64% | 22 |