| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Case Report
Volume 5, Number 2, April 2014, pages 68-71
Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
Table
| Author | Age | Sex | Type | Paraprotein | Karyotype | Treatment | Survival |
|---|---|---|---|---|---|---|---|
| *Patient had pancytopenia for 3 years prior to the diagnosis. †Patient had pancytopenia for 5 years prior to the diagnosis. **Cases described in Rosner and Grunwald [17]. K: kappa light chain; λ: lambda light chain; F: female; M: male; NA: not available. | |||||||
| Kim [3] | 51 | M | Myelo blastic | Κ | Complex | Bortezomib; ara-C and idarubicin; ara-C and mitoxantrone, allo-SCT | Alive at 421 days |
| Shukla [4] | 58 | F | Myelo blastic | IgG/λ | NA | Anthracycline/ara-C | 1 month |
| Attili [5] | 57 | M | Myelo blastic | IgG/K | 46, XY/t(8;21) | NA | Sepsis on day 7 |
| Luca [6] | 77 | M | Monocytic | IgG/λ | Monosomy 13, structural changes of Chr 1, 20q- | NA | One month |
| Raz [7] | 68 | M | Monoblastic | IgG/K | “No bizarre chromosomal changes” | Cyclophosphamide followed 2 months later by melphalan followed by vincristine, melphalan, cyclophoside, prednisone | 2.5 years |
| Cleary [8] | 64 | M | Myelomonocytic | IgA/K | 46 XY | Cytarabine and daunorubicin | 4 months |
| Tursz [9] | 77* | M | Myeloblastic | IgA | NA | NA | NA |
| 74† | M | Myeloblastic | IgG//λ | NA | Mercaptopurine | Few months | |
| Rosner [10] | 79 | M | Myelomonocytic | NA | NA | Cyclophosphamide 150 mg/day and testosterone for 6 weeks, which was stopped then after. Methotrexate and prednisone once AML was diagnosed 5 months later | Died shortly after the diagnosis of AML |
| Taddeini [11]** | 73 | M | NA | IgG//λ | NA | Combination chemotherapy | About 14 weeks |
| Parker [12]** | 79 | M | NA | IgG | Normal | Cytarabine and daunorubicin; then after, 5 days of prednisone and melphalan since plasma cell increased in repeat bone marrow exam | About 12 weeks |
| Kastanas [13]** | 70 | M | NA | IgG | NA | NA | NA |
| Annino [14]** | 74 | M | Myelomonocytic | IgG/K | Hypodiploidy and marker chromosome | NA | NA |
| Vallantin [15]** | 66 | M | Myeloblastic | IgG/λ | NA | NA | NA |
| Parapia [16]** | 79 | M | IgG/λ | Normal | Cytarabine, daunorubicin and 6-thioguanine | About 6 weeks | |