World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 5, Number 1, February 2014, pages 7-13


Age Influences Likelihood of Pancreatic Cancer Treatment, but not Outcome

Figures

Figure 1.
Figure 1. Comparison of survival in patients younger than and older than 50 years old who were diagnosed with exocrine pancreatic tumors (solid line: patients ≤ 50 years old; dashed line: patients > 50 years old).
Figure 2.
Figure 2. Comparison of survival in patients younger than and older than 50 years old who were diagnosed with endocrine pancreatic tumors (solid line: patients ≤ 50 years old; dashed line: patients > 50 years old).

Tables

Table 1. Demographic and Tumor Characteristics for Pancreas Cancer Patients ≤ 50 Years Old and > 50 Years Old
 
Age ≤ 50 years (%), N = 53Age > 50 years (%), N = 254P value
Age44 ± 5.767.2 ± 9.3< 0.001
Gender
  Male33 (64)143 (57)0.372
  Female19 (37)109 (43)
Race
  Caucasian34 (92)158 (93)0.585
  African American3 (8)9 (5)
  Other0 (0)3 (2)
Location of tumor (%)0.541
  Head of pancreas34( 63)146 (58)
  Body/tail of pancreas12 (23)59 (23)
  Unknown7 (13)49 (19)
Exocrine tumor stage0.516
  I3 (8)16 (7)
  II12 (30)53 (25)
  III8 (20)24 (11)
  IV17 (42)123 (57)

 

Table 2. Treatment and Outcomes in Younger Versus Older Pancreas Cancer Patients
 
Age ≤ 50 (%)Age > 50 (%)P value
Surgery11 (22)51 (20)0.911
Chemotherapy33 (62)104 (41)0.005
Radiation15 (28)39 (15)0.025
Number still alive4 (8)19 (8)0.987
Overall survival (months)24.2140.06

 

Table 3. Age Comparison for Exocrine and Endocrine Tumors
 
Patient population≤ 50 years (%)> 50 years (%)P value
  Exocrine41 (15)237 (85)
  Endocrine12 (41)17 (59)
Age
  Exocrine45 ± 4.767.4 ± 9.3< 0.001
  Endocrine40.7 ± 7.664 ± 8.2< 0.001
Location of tumor
  Exocrine0.24
    Head of pancreas30 (73)142 (60)
    Body/tail of pancreas7 (17)51 (21)
    Unknown4 (10)44 (19)
  Endocrine0.84
    Head of pancreas4 (33)4 (24)
    Body/tail of pancreas5 (39)8 (47)
    Unknown3 (38)5 (29)
Surgery performed
  Exocrine7 (17)41 (17)0.97
  Endocrine4 (33)10 (59)0.23
Chemotherapy
  Exocrine28 (68)98 (42)0.001
  Endocrine5 (42)6 (35)0.73
Radiation therapy
  Exocrine15 (37)39 (17)0.003
  Endocrine00
Number still alive
  Exocrine0 (0)11 (5)0.16
  Endocrine4 (33)8 (47)0.46
Overall survival (months)
  Exocrine9.611.20.64
  Endocrine74.347.60.19