Exposure to Temozolmide in the First Trimester of Pregnancy in a Young Woman With Glioblastoma Multiforme

Bernadette Nolan, Madhuri Balakrishna, Mathew George

Abstract


Literature on the outcome of pregnancy with first trimester exposure to Temozolomide is limited. We describe the case of a young woman with Glioblastoma Multiforme who was exposed to Temozolomide during her first trimester of pregnancy and subsequently delivered a healthy term newborn. At six months of age, the child remains healthy with no evidence of Temozolomide related effects.




World J Oncol. 2012;3(6):286-287
doi: https://doi.org/10.4021/wjon570w

Keywords


Temozolomide; Glioblastoma multiforme; Early pregnancy; First trimester pregnancy; Teratogenicity; Malformations; Complications

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