World Journal of Oncology

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Editor-in-Chief
Kazuaki Takabe, MD, PhD, FACS
Professor, Alfiero Foundation Chair, and Clinical Chief of Breast Surgery in Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center in Buffalo, New York, USA
Professor of Surgery with Tenure in Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, the State University of New York, USA
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ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope

Indexed and covered: PubMed, PubMed Central, Scopus, Elsevier Embase, Web of Science, Chemical Abstract (CA), EBSCO, Worldcat, Google, Google Scholar.

JCR Impact Factor (JIF 2022): 5.2. Q1, 47/317 (85%) Oncology (Rank by Journal Citation Indicator)

CiteScore (2022): 5; Scopus Scimago Journal Rank: 82/375 (Oncology), Q1


Journal archiving and digital preservation:
Portico


Highlights

  • Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells

    The dynamic changes between glycolysis and oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) output, along with glucose, glutamine, and fatty acid utilization, etc., lead to the maintenance and selection of growth advantageous to tumor cell subgroups in an environment of iron starvation and hypoxia.

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  • Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis

    Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.

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  • Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis

    The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.

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  • Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment

    The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.

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  • Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy

    Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).

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Featured

 

 

Featured

 

Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States
Robotic gastrectomy (RG) has been increasingly used for treatment of gastric cancer in the United States. However, it is unknown if there has been a nationwide improvement of short-term safety outcomes and oncological quality metrics over time. Full Text

Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line, ICC-X2
Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignant tumor of the biliary tract that is prone to recurrence and metastasis and is characterized by poor sensitivity to chemotherapy and overall prognosis. Full Text


Key Clinical Image

Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. Full Text


Current Issue

 


Vol. 15, No. 1, Feb 2024

Table of Contents

Review

Autotaxin and Lysophosphatidate Signaling: Prime Targets for Mitigating Therapy Resistance in Breast Cancer Abstract HTML PDF
Matthew G.K. Benesch, Xiaoyun Tang, David N. Brindley, Kazuaki Takabe 1-13
doi: https://doi.org/10.14740/wjon1762
Autoimmune Thyroid Disease and Differentiated Thyroid Carcinoma: A Review of the Mechanisms That Explain an Intriguing and Exciting Relationship Abstract HTML PDF
Hernando Vargas-Uricoechea 14-27
doi: https://doi.org/10.14740/wjon1728
Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells Abstract HTML PDF
Rui Wang, Aashiq Hussain, Quan Quan Guo, Xiao Wei Jin, Miao Miao Wang 28-37
doi: https://doi.org/10.14740/wjon1739

Original Article

Viability Profiles of Normal and Cancer Bladder Cells With Metformin, Nitrate and Adenosine Monophosphate-Activated Protein Kinase Inhibitor Abstract HTML PDF
Haitham Abdelmoaty, Sonya Good, Tuan Phan 38-44
doi: https://doi.org/10.14740/wjon1590
Identification and Validation of a Novel Anoikis-Related Gene Signature for Predicting Survival in Patients With Serous Ovarian Cancer Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 Suppl8 Suppl9 Suppl10
Hong Yu Deng, Li Wen Zhang, Fa Qing Tang, Ming Zhou, Meng Na Li, Lei Lei Lu, Ying Hua Li 45-57
doi: https://doi.org/10.14740/wjon1714
Radiomics of Preoperative Multi-Sequence Magnetic Resonance Imaging Can Improve the Predictive Performance of Microvascular Invasion in Hepatocellular Carcinoma Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6
Wan Min Liu, Xing Yu Zhao, Meng Ting Gu, Kai Rong Song, Wei Zheng, Hui Yu, Hui Lin Chen, Xiao Wen Xu, Xiang Zhou, Ai E Liu, Ning Yang Jia, Pei Jun Wang 58-71
doi: https://doi.org/10.14740/wjon1731
The Addition of Atezolizumab to Chemotherapy in Non-Small Cell Lung Cancer: A Trial-Based Review and Meta-Analysis Abstract HTML PDF
Nadya Keumala Fitri, Bahagia Willibrordus Maria Nainggolan, Naufal Nandita Firsty, Andika Pradana, Dina Keumala Sari 72-80
doi: https://doi.org/10.14740/wjon1701
Application of Machine Learning and Deep EfficientNets in Distinguishing Neonatal Adrenal Hematomas From Neuroblastoma in Enhanced Computed Tomography Images Abstract HTML PDF
Lu Lu Xie, Ying Gong, Kui Ran Dong, Chun Shen, Bo Duan, Rui Dong 81-89
doi: https://doi.org/10.14740/wjon1744
Multicentricity and the Risk of Recurrence/Persistence After Laser Vaporization for High-Grade Vulvar and Vaginal Intraepithelial Neoplasia Abstract HTML PDF
Sathone Boonlikit, Punyacha Tangterdchanakit 90-99
doi: https://doi.org/10.14740/wjon1743
Inhibiting the m6A Reader IGF2BP3 Suppresses Ovarian Cancer Cell Growth via Regulating PLAGL2 mRNA Stabilization Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7
Tian Tian Dai, Yi Ze Li, Hui Ting Hu, Yong Mei Zhao, Hong Yan Peng, Wen Dong Bai, Jing Wen Wang 100-113
doi: https://doi.org/10.14740/wjon1747
Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line, ICC-X2 Abstract HTML PDF
Hao Xu, Chang Peng Chai, Huan Tang, Yuan Hui Su, Cheng Yu, Lu Li, Zhen Zhen Ye, Zheng Feng Wang, Jin Jing Hu, Wei Luo, Hui Zhang, Xin Miao, Wen Ce Zhou 114-125
doi: https://doi.org/10.14740/wjon1757
Treatment Patterns and Survival Outcomes in Patients With Stage T1-2N0M0 Small Cell Lung Cancer Undergoing Surgery: A Retrospective Cohort Study Abstract HTML PDF
Jiang Qiong Huang, Huan Wei Liang, Yang Liu, Long Chen, Su Pei, Bin Bin Yu, Wei Huang, Xin Bin Pan 126-135
doi: https://doi.org/10.14740/wjon1765

Short Communication

Clinical Outcomes of Curative Intent Radiotherapy by Helical Tomotherapy for Laryngeal Squamous Cell Carcinoma: A Retrospective Analysis in a Tertiary Referral Center Abstract HTML PDF
Atsuto Katano, Hideomi Yamashita 136-142
doi: https://doi.org/10.14740/wjon1638

Case Report

Significance of Beta Human Chorionic Gonadotropin in Predicting Disease Progression in Uterine Leiomyosarcoma Abstract HTML PDF
Abdulla Alzibdeh, Issa Mohamad, Maysa Al-Hussaini, Samer Salah, Abdalgani Jaradat, Ramiz Abuhijlih, Fawzi Abuhijla 143-148
doi: https://doi.org/10.14740/wjon1748
 

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World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.                     
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