World Journal of Oncology


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Kazuaki Takabe, MD, PhD, FACS
Professor, Alfiero Foundation Chair, and Clinical Chief of Breast Surgery in Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center in Buffalo, New York, USA
Professor of Surgery with Tenure in Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, the State University of New York, USA

ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope

Indexed and covered: PubMed, PubMed Central, Scopus, Elsevier Embase, Web of Science, Chemical Abstract (CA), EBSCO, Worldcat, Google, Google Scholar.

JCR Impact Factor (JIF 2022): 5.2. Q1, 47/317 (85%) Oncology (Rank by Journal Citation Indicator)

CiteScore (2022): 5; Scopus Scimago Journal Rank: 82/375 (Oncology), Q1

Journal archiving and digital preservation:


  • Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment

    The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.

  • Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy

    Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).

  • Improving Gastrointestinal Cancer Care by Enhanced Recovery Protocol Implementation

    Enhanced recovery protocols (ERPs) have become the standard of care for patients undergoing elective small bowel surgeries but have not yet been adequately studied in community hospitals. In this study, a multidisciplinary ERP was developed and implemented at a community hospital to include minimal anesthesia, early ambulation and enteral alimentation, and multimodal analgesia.

  • Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Cancer Antigen 125, Prostate-Specific Antigen and Other Cancer Markers: A Primer on Commonly Used Cancer Markers

    Cancer markers are molecules produced by cancer cells which may serve to identify the presence of cancer. Cancer markers can be differentiated as serum-based, radiology-based and tissue-based.

  • Glycine Decarboxylase Suppresses the Renal Cell Carcinoma Growth and Regulates Its Gene Expressions and Functions

    Glycine decarboxylase (GLDC), a key metabolic enzyme, participates in the regulation of the glycine metabolic pathway. Differential expression of GLDC is linked to the malignant growth of renal cell carcinoma (RCC) and may regulate tumor progression through other genes.







Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States
Robotic gastrectomy (RG) has been increasingly used for treatment of gastric cancer in the United States. However, it is unknown if there has been a nationwide improvement of short-term safety outcomes and oncological quality metrics over time. Full Text

The Role of Hemophilus influenzae Infection and Its Relationship With Colorectal Cancer
Hemophilus influenzae is a gram-negative coccobacillus. Non-typeable H. influenzae infection is a significant cause of disease that activates the inflammatory pathway involving the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome. Full Text

Key Clinical Image

Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. Full Text

Current Issue


Vol. 14, No. 5, Oct 2023

Table of Contents


Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7
Nooraldin Merza, Sabeeh Khawar Farooqui, Sophia Haroon Dar, Tony Varughese, Rehmat Ullah Awan, Lamaan Qureshi, Saad Ali Ansari, Hadi Qureshi, Jamie Mcilvaine, Ishaan Vohra, Yusuf Nawras, Abdallah Kobeissy, Mona Hassan 325-339
Biology of Mesothelin and Clinical Implications: A Review of Existing Literature Abstract HTML PDF
Brendan L. Hagerty, Kazuaki Takabe 340-349
Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment Abstract HTML PDF
Dao Qi Zhu, Chao Su, Jing Jun Li, Ai Wu Li, Ying Luv, Qin Fan 350-357

Original Article

The Olfaction Ability of Medical Detection Canine to Detect Prostate Cancer From Urine Samples: Progress Captured in Systematic Review and Meta-Analysis Abstract HTML PDF
Syah Mirsya Warli, Naufal Nandita Firsty, Adrian Joshua Velaro, Zaimah Zulkarnaini Tala 358-370
Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States Abstract HTML PDF
Yuki Hirata, Yi-Ju Chiang, Paul Mansfield, Brian D. Badgwell, Naruhiko Ikoma 371-381
Familial Risk and Interaction With Smoking and Alcohol Consumption in Bladder Cancer: A Population-Based Cohort Study Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4
Hyun Jung Kim, Kyoung-Hoon Kim, Sung Won Lee, Heather Swan, Sayada Zartasha Kazmi, Young Shin Kim, Kyeong Uoon Kim, Minjung Kim, Jaewoo Cha, Taeuk Kang, Hoo Jae Hann, Hyeong Sik Ahn 382-391
The Impact of Omitting 5-FU Bolus From mFOLFOX6 Chemotherapy Regimen on Hematological Adverse Events Among Patients With Metastatic Colorectal Cancer Abstract HTML PDF
Nutthada Areepium, Bannawich Sapapsap 392-400
Improving Value in Colorectal Cancer Care: An Economic Analysis of Enhanced Recovery Protocols at a Community Hospital Abstract HTML PDF
Lexi Frankel, Amalia D. Ardeljan, Ali Rashid, Abhishek Nair, Kazuaki Takabe, Omar M. Rashid 401-405
Development of a Machine Learning-Based Prognostic Model for Hormone Receptor-Positive Breast Cancer Using Nine-Gene Expression Signature Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4
Takashi Takeshita, Hirotaka Iwase, Rongrong Wu, Danya Ziazadeh, Li Yan, Kazuaki Takabe 406-422
Tumor Markers as Predictors of Acute Kidney Injury Incidence and Staging of the Muscle-Invasive Bladder Cancer Receiving Chemoradiation Therapy Abstract HTML PDF
Syah Mirsya Warli, Fauriski Febrian Prapiska, Dewi Indah Sari Siregar, Ilham Ari Seja 423-429
Oral Administration of Glucosylceramide Suppresses Tumor Growth by Affecting the Ceramide/Sphingosine-1-Phosphate Balance in Breast Cancer Tissue Abstract HTML PDF
Kazuki Moro, Hiroshi Ichikawa, Yu Koyama, Shun Abe, Haruka Uchida, Kana Naruse, Yasuo Obata, Junko Tsuchida, Chie Toshikawa, Mayuko Ikarashi, Yusuke Muneoka, Kohei Miura, Yosuke Tajima, Yoshifumi Shimada, Takashi Kobayashi, Jun Sakata, Kazuaki Takabe, Toshifumi Wakai 430-437

Case Report

Multiple Myeloma Rather Than Metastatic Lung Cancer: An Unexpected Cause of Spinal Cord Compression Abstract HTML PDF
Chang Jun Chen, Ting Bin Yan, Ya Di Liu, Yan Wang, Xin Zhao, Yu Bin Qi, Ying Guang Wu, Kai Ning Zhang, Yan Jun Ren, Yun Yang 438-442

Letter to the Editor

Are the Number of Operations Appropriate to Define a High-Quality Breast Cancer Center? Abstract HTML PDF
Paolo Tralongo, Roberto Bordonaro, Francesco Ferrau, Giovanni Trombatore 443-445

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World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.                     
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