World Journal of Oncology


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Kazuaki Takabe, MD, PhD, FACS
Professor, Alfiero Foundation Chair, and Clinical Chief of Breast Surgery in Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center in Buffalo, New York, USA
Professor of Surgery with Tenure in Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, the State University of New York, USA

ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope

Indexed and covered: PubMed, PubMed Central, Scopus, Elsevier Embase, Web of Science (ESCI), Chemical Abstract (CA), EBSCO, Worldcat, Google, Google Scholar.
JCR Impact Factor: available June 2023.
Scopus Scimago Journal Rank (2021): 116/369 (Oncology), Q2

Journal archiving and digital preservation:

COVID-19 and Long COVID

COVID-19 and Post COVID-19 Condition (Long COVID)
The COVID-19 outbreak presents the unprecedented challenge for world public and medical practitioners and health care providers, the post COVID-19 condition (or long COVID) includes long term symptoms which may persist for months or years after SARS-CoV-2 infection. We will consider submissions related to all aspects of COVID-19 and Long COVID, and process the manuscripts in priority.
Collection of COVID-19 articles.


  • Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Cancer Antigen 125, Prostate-Specific Antigen and Other Cancer Markers: A Primer on Commonly Used Cancer Markers

    Cancer markers are molecules produced by cancer cells which may serve to identify the presence of cancer. Cancer markers can be differentiated as serum-based, radiology-based and tissue-based.

  • Glycine Decarboxylase Suppresses the Renal Cell Carcinoma Growth and Regulates Its Gene Expressions and Functions

    Glycine decarboxylase (GLDC), a key metabolic enzyme, participates in the regulation of the glycine metabolic pathway. Differential expression of GLDC is linked to the malignant growth of renal cell carcinoma (RCC) and may regulate tumor progression through other genes.

  • Cancer Progression Is not Different in Mice of Different Gender Inoculated With Cells of the Triple-Negative 4T1 Breast Cancer Model

    Breast cancer in men is a rare and poorly studied disease, and its treatment is based on women breast cancer studies. However, clinical outcome is not the same in men and women.

  • N6-Methyladenosine RNA Modification Landscape in the Occurrence and Recurrence of Nasopharyngeal Carcinoma

    Nasopharyngeal carcinoma (NPC) is a type of squamous head and neck cancer with variable geographic distributions, with the highest incidence in Southeast Asia. Its primary treatment is radiotherapy due to its high radio sensitivity.

  • Abdominopelvic Lymphatic Drainage Area Irradiation for Consolidative Radiotherapy of Advanced Ovarian Carcinoma: Analysis of Clinical Application Efficacy and Dosimetric Verification

    The aim of the study was to evaluate the efficacy of abdominopelvic lymphatic drainage area irradiation (APLN), instead of whole abdominal radiotherapy (WART), in the consolidative radiotherapy of advanced ovarian carcinoma patients.







The Dimensions of Reports From Around the World That Address Diversity in Oncology
Reproducibility is one of the major principles of science. Scientific findings should be reproducible anywhere in the world. Based on this principle, basic researchers tend to assume that cancer biology is the same for all populations regardless of location, race, or ethnicity. Full Text

Real-World Experience of Adults With Acute Myeloid Leukemia on Hypomethylating Agents With or Without Venetoclax at a Comprehensive Cancer Center
Venetoclax (VEN) in combination with hypomethylating agent (HMA) therapy is a standard treatment option for patients with newly diagnosed acute myeloid leukemia (AML); however, data are limited in the relapsed or refractory (R/R) populations and in those with poor-risk disease. Full Text

Key Clinical Image

Non-GCB Diffuse Large B-Cell Lymphoma With an Atypical Disease Course: A Case Report and Clinical Exome Analysis
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid tumor among other non-Hodgkin lymphomas (30-40% of all cases). This type of lymphoma is characterized by significant differences in treatment response and the heterogeneity of clinical traits. Full Text

Current Issue


Vol. 14, No. 1, Feb 2023

Table of Contents


Biomarker Research in World Journal of Oncology Abstract HTML PDF
Kazuaki Takabe, Matthew G.K. Benesch 1-3


Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Cancer Antigen 125, Prostate-Specific Antigen and Other Cancer Markers: A Primer on Commonly Used Cancer Markers Abstract HTML PDF
Shreya Desai, Achuta K. Guddati 4-14
Adult Primary Retroperitoneal Lymphangioma: Updated Facts Abstract HTML PDF
Subhi Mansour, Yoram Kluger, Safi Khuri 15-20
Cutaneous Malignant Melanoma Presenting as an Isolated Splenic Metastasis: An Update Abstract HTML PDF
Saeed Ali Alshehri, Toka M.R.A. Hussein, Mahmoud R.A. Hussein 21-25
Postoperative Chemotherapy After Surgical Resection of Metachronous Metastases of Colorectal Cancer: A Systematic Review Abstract HTML PDF
Sevindzh Evdokimova, Anna Kornietskaya, Larisa Bolotina, Dmitriy Sidorov, Andrey Kaprin 26-31

Original Article

Incidence of Breast Cancer and Enterococcus Infection: A Retrospective Analysis Abstract HTML PDF
Matthew Cardeiro, Amalia D. Ardeljan, Lexi Frankel, Enoch Kim, Kazuaki Takabe, Omar M. Rashid 32-39
Real-World Experience of Adults With Acute Myeloid Leukemia on Hypomethylating Agents With or Without Venetoclax at a Comprehensive Cancer Center Abstract HTML PDF
Tracelyn Freeman, Kiersten Williams, Marcin Puto, Allyson Waller, Eric M. McLaughlin, James S. Blachly, Julianna Roddy 40-50
Uses of Vascular Endothelial Growth Factor C as a Lung Adenocarcinoma Prognostic Biomarker Abstract HTML PDF
Shi Chen, Ting Yu Pan, Xiao Wu, Tian Li, Yu Wei, Hai Lang He, Xian Mei Zhou, Qian Wang, Ji Ping Zhu 51-59
Estradiol Levels and Chemotherapy in Breast Cancer Patients: A Prospective Clinical Study Abstract HTML PDF
Widyanti Soewoto, Nunik Agustriani 60-66
Association Between Expression of Vitamin D Receptor and Insulin-Like Growth Factor 1 Receptor Among Breast Cancer Patients Abstract HTML PDF
Ayaa Alnimer, Poorna Manasa Bhamidimarri, Iman M. Talaat, Noura Alkhayaal, Abdalla Eltayeb, Nival Ali, Salah Abusnana, Rifat Hamoudi, Riyad Bendardaf 67-74
High Body Mass Index Was Associated With Human Epidermal Growth Factor Receptor 2-Positivity, Histological Grade and Disease Progression Differently by Age Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6
Di Zhao, Xiaoyan Wang, Narasimha M. Beeraka, Runze Zhou, Haohao Zhang, Yanxia Liu, Yinghui Zhang, Ying Zhang, Guijun Qin, Junqi Liu 75-83
The Impact of DTYMK as a Prognostic Marker in Colorectal Cancer Abstract HTML PDF
Abdulaziz A. Aloliqi, Abdul-Fattah Fararjeh, Ali Al-Khader, Ezidin Kaddumi, Alaa Abdulaziz Eisa, Weam Jaradat 84-93
Nephrolithiasis-Associated Renal Cell Carcinoma in Patients Who Underwent Nephrectomy: A Single-Center Experience Abstract HTML PDF
Syah Mirsya Warli, Ben Julian Mantiri, Bungaran Sihombing, Ginanda Putra Siregar, Fauriski Febrian Prapiska 94-100

Case Report

Long-Term Responders to Erlotinib for Pulmonary Adenocarcinoma With Wild-Type Epidermal Growth Factor Receptor: Two Case Reports and a Single-Institutional Retrospective Study Abstract HTML PDF
Seigo Minami, Nao Shoshihara 101-107

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World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.                     
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