World Journal of Oncology


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Kazuaki Takabe, MD, PhD, FACS
Professor, Alfiero Foundation Chair, and Clinical Chief of Breast Surgery in Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center in Buffalo, New York, USA
Professor of Surgery with Tenure in Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, the State University of New York, USA

ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope

Indexed and covered: PubMed, PubMed Central, Scopus, Elsevier Embase, Web of Science, Chemical Abstract (CA), EBSCO, Worldcat, Google, Google Scholar.

JCR Impact Factor (JIF 2022): 5.2. Q1, 47/317 (85%) Oncology (Rank by Journal Citation Indicator)

CiteScore (2022): 5; Scopus Scimago Journal Rank: 82/375 (Oncology), Q1

Journal archiving and digital preservation:


  • Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis

    Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.

  • Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis

    The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.

  • Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment

    The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.

  • Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy

    Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).

  • Improving Gastrointestinal Cancer Care by Enhanced Recovery Protocol Implementation

    Enhanced recovery protocols (ERPs) have become the standard of care for patients undergoing elective small bowel surgeries but have not yet been adequately studied in community hospitals. In this study, a multidisciplinary ERP was developed and implemented at a community hospital to include minimal anesthesia, early ambulation and enteral alimentation, and multimodal analgesia.







Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States
Robotic gastrectomy (RG) has been increasingly used for treatment of gastric cancer in the United States. However, it is unknown if there has been a nationwide improvement of short-term safety outcomes and oncological quality metrics over time. Full Text

The Role of Hemophilus influenzae Infection and Its Relationship With Colorectal Cancer
Hemophilus influenzae is a gram-negative coccobacillus. Non-typeable H. influenzae infection is a significant cause of disease that activates the inflammatory pathway involving the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome. Full Text

Key Clinical Image

Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. Full Text

Current Issue


Vol. 14, No. 6, Dec 2023

Table of Contents


Malignant Transformation of Long-Standing Ileal Crohn’s Disease Likely Favors Signet Ring Cell Adenocarcinoma Histology Abstract HTML PDF Suppl1 Suppl2
Matthew G.K. Benesch, Erek D. Nelson, Shalana B.L. O’Brien 447-456

Original Article

The Role of Crohn Disease on Breast Cancer Incidence: A Clinical Analysis Abstract HTML PDF
Raina K. Patel, Lexi Frankel, Matthew Cardeiro, Wade Hansen, Kazuaki Takabe, Omar M. Rashid 457-463
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis Abstract HTML PDF
Rui Wang, Shu Ling Liu, Shu Ling Liu, Quan Quan Guo, Shu Ling Liu, Xiao Hong Shi, Mei Mei Ma 464-475
Construction and Validation of a Novel Nomogram for Predicting the Risk of Metastasis in a Luminal B Type Invasive Ductal Carcinoma Population Abstract HTML PDF
Xu Dong Zhu, Jia Hui Yu, Fu Lu Ai, Yue Wang, Wu Lv, Gui Lin Yu, Xian Kui Cao, Jie Lin 476-487
Prevalence and Prognosis of Secondary Genetic Aberrations Among Patients With Core Binding Factor Acute Myeloid Leukemia: A Mitelman Database Analysis Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5
Renzo Martin Chapilliquen Ramirez, Mariana Teresa de Jesus Corbacho Pachas, Richard Junior Zapata Dongo 488-498
Efficiency of the Robotic Platform in Improving the Rate of Sphincter Preservation in Patients With Mid and Low Rectal Cancer Abstract HTML PDF
Thalia Petropoulou, Kassiani Theodoraki, Panagiota Kitsanta, Shwan Amin 499-504
Development and Validation of Nomograms Based on Nutritional Risk Index for Predicting Extracapsular Extension and Seminal Vesicle Invasion in Patients Undergoing Radical Prostatectomy Abstract HTML PDF
Ze Nan Liu, Zi Ang Li, Ji De He, Jia Long Wu, Lei Qiu, Zhen Kun Zhao, Min Lu, Hai Bi, Jian Lu 505-517
Addition of Olaparib to the New Hormonal Agent Regimen for Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis Abstract HTML PDF
Syah Mirsya Warli, Adrian Joshua Velaro, Naufal Nandita Firsty, Zaimah Zulkarnaini Tala 518-528
Efficacy of First-Line Immunotherapy Combined With Chemotherapy in Extensive-Stage Small Cell Lung Cancer Patients With Different Brain Metastases Status: A Systematic Review and Meta-Analysis Abstract HTML PDF
Wen Hua Zhao, Shou Feng Wang, Cui Yun Su, Xin Bin Pan 529-539
Vasopressin Analog [V4Q5]dDAVP Exerts Cooperative Anticancer Effects in Combination With Low-Dose 5-Fluorouracil on Aggressive Colorectal Cancer Models Abstract HTML PDF Suppl1 Suppl2 Suppl3
Natasha T. Sobol, Luisina M. Solerno, Candela Llavona, Daniel F. Alonso, Juan Garona 540-550
Clinicopathological Characteristics and Prognosis of Triple-Negative Apocrine Carcinoma: A Case-Control Study Abstract HTML PDF
Chiho Suzuki, Akimitsu Yamada, Kei Kawashima, Mahato Sasamoto, Yoshie Fujiwara, Shoko Adachi, Masanori Oshi, Tomoko Wada, Shinya Yamamoto, Kazuhiro Shimada, Ikuko Ota, Kazutaka Narui, Sadatoshi Sugae, Daisuke Shimizu, Mikiko Tanabe, Takashi Chishima, Yasushi Ichikawa, Takashi Ishikawa, Itaru Endo 551-557
Genetically Predicted Causal Effects of Gut Microbiota and Gut Metabolites on Digestive Tract Cancer: A Two-Sample Mendelian Randomization Analysis Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 Suppl8 Suppl9 Suppl10 Suppl11 Suppl12 Suppl13 Suppl14 Suppl15
Xu Jia Li, Meng Ge Gao, Xu Xian Chen, Yu Ming Rong, Ling Li Huang 558-569

Case Report

Catch the Calcium: T-Cell Histiocyte-Rich B-Cell Lymphoma Presenting as Hypercalcemia Abstract HTML PDF
Richard K. Okeke, Gabriella A. Harmon, Ijeoma G. Okeke, Jake W. Schuler, Sahana J. Sangappa, Jonathan S. Harmon, Evgeniya Angelova, Xiu Sun, Angelo A. Chinnici 570-574
Dramatic Improvement of Pulmonary Tumor Thrombotic Microangiopathy in a Breast Cancer Patient Treated With Bevacizumab Abstract HTML PDF
Aki Kimura, Akimitsu Yamada, Masanori Oshi, Mina Nakayama, Naohiro Komura, Teruyasu Sugano, Shinya Yamamoto, Kazutaka Narui, Itaru Endo 575-579
Osteoblastic Bone Reaction Developing During Treatment With Sintilimab and Bevacizumab in a Patient With KRASG12V-Mutant Lung Adenocarcinoma Abstract HTML PDF
Chang Jun Chen, Xin Zhao, Jing Wen Zhao, Xiao Jie Ma, Wei Hua Xu, Yu Bin Qi, Jing Kun Li, Qing Wei Ma, Lei Zhang, Yun Yang 580-583
Borderline Phyllodes Tumor in a Child Abstract HTML PDF
Esperanza Millan-Arreola, Diego Alberto Lozano-Jaramillo, Aida Tello De Meneses-Salazar, Oscar Omar Esquer-Cota, Luz Adriana Lavara-Miranda, Miguel Alfonso Valenzuela-Espinoza 584-588

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World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.                     
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