Editor-in-Chief ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope |
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- Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells
The dynamic changes between glycolysis and oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) output, along with glucose, glutamine, and fatty acid utilization, etc., lead to the maintenance and selection of growth advantageous to tumor cell subgroups in an environment of iron starvation and hypoxia.
Read More >> - Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis
Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.
Read More >> - Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis
The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.
Read More >> - Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment
The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.
Read More >> - Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy
Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).
Read More >>
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Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States | Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line, ICC-X2 | |||
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Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases |
Current Issue |
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Vol. 15, No. 1, Feb 2024
Table of Contents
Review
Autotaxin and Lysophosphatidate Signaling: Prime Targets for Mitigating Therapy Resistance in Breast Cancer | Abstract HTML PDF |
Matthew G.K. Benesch, Xiaoyun Tang, David N. Brindley, Kazuaki Takabe | 1-13 |
doi: https://doi.org/10.14740/wjon1762 |
Autoimmune Thyroid Disease and Differentiated Thyroid Carcinoma: A Review of the Mechanisms That Explain an Intriguing and Exciting Relationship | Abstract HTML PDF |
Hernando Vargas-Uricoechea | 14-27 |
doi: https://doi.org/10.14740/wjon1728 |
Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells | Abstract HTML PDF |
Rui Wang, Aashiq Hussain, Quan Quan Guo, Xiao Wei Jin, Miao Miao Wang | 28-37 |
doi: https://doi.org/10.14740/wjon1739 |
Original Article
Viability Profiles of Normal and Cancer Bladder Cells With Metformin, Nitrate and Adenosine Monophosphate-Activated Protein Kinase Inhibitor | Abstract HTML PDF |
Haitham Abdelmoaty, Sonya Good, Tuan Phan | 38-44 |
doi: https://doi.org/10.14740/wjon1590 |
Identification and Validation of a Novel Anoikis-Related Gene Signature for Predicting Survival in Patients With Serous Ovarian Cancer | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 Suppl8 Suppl9 Suppl10 |
Hong Yu Deng, Li Wen Zhang, Fa Qing Tang, Ming Zhou, Meng Na Li, Lei Lei Lu, Ying Hua Li | 45-57 |
doi: https://doi.org/10.14740/wjon1714 |
Radiomics of Preoperative Multi-Sequence Magnetic Resonance Imaging Can Improve the Predictive Performance of Microvascular Invasion in Hepatocellular Carcinoma | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 |
Wan Min Liu, Xing Yu Zhao, Meng Ting Gu, Kai Rong Song, Wei Zheng, Hui Yu, Hui Lin Chen, Xiao Wen Xu, Xiang Zhou, Ai E Liu, Ning Yang Jia, Pei Jun Wang | 58-71 |
doi: https://doi.org/10.14740/wjon1731 |
The Addition of Atezolizumab to Chemotherapy in Non-Small Cell Lung Cancer: A Trial-Based Review and Meta-Analysis | Abstract HTML PDF |
Nadya Keumala Fitri, Bahagia Willibrordus Maria Nainggolan, Naufal Nandita Firsty, Andika Pradana, Dina Keumala Sari | 72-80 |
doi: https://doi.org/10.14740/wjon1701 |
Application of Machine Learning and Deep EfficientNets in Distinguishing Neonatal Adrenal Hematomas From Neuroblastoma in Enhanced Computed Tomography Images | Abstract HTML PDF |
Lu Lu Xie, Ying Gong, Kui Ran Dong, Chun Shen, Bo Duan, Rui Dong | 81-89 |
doi: https://doi.org/10.14740/wjon1744 |
Multicentricity and the Risk of Recurrence/Persistence After Laser Vaporization for High-Grade Vulvar and Vaginal Intraepithelial Neoplasia | Abstract HTML PDF |
Sathone Boonlikit, Punyacha Tangterdchanakit | 90-99 |
doi: https://doi.org/10.14740/wjon1743 |
Inhibiting the m6A Reader IGF2BP3 Suppresses Ovarian Cancer Cell Growth via Regulating PLAGL2 mRNA Stabilization | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 |
Tian Tian Dai, Yi Ze Li, Hui Ting Hu, Yong Mei Zhao, Hong Yan Peng, Wen Dong Bai, Jing Wen Wang | 100-113 |
doi: https://doi.org/10.14740/wjon1747 |
Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line, ICC-X2 | Abstract HTML PDF |
Hao Xu, Chang Peng Chai, Huan Tang, Yuan Hui Su, Cheng Yu, Lu Li, Zhen Zhen Ye, Zheng Feng Wang, Jin Jing Hu, Wei Luo, Hui Zhang, Xin Miao, Wen Ce Zhou | 114-125 |
doi: https://doi.org/10.14740/wjon1757 |
Treatment Patterns and Survival Outcomes in Patients With Stage T1-2N0M0 Small Cell Lung Cancer Undergoing Surgery: A Retrospective Cohort Study | Abstract HTML PDF |
Jiang Qiong Huang, Huan Wei Liang, Yang Liu, Long Chen, Su Pei, Bin Bin Yu, Wei Huang, Xin Bin Pan | 126-135 |
doi: https://doi.org/10.14740/wjon1765 |
Short Communication
Clinical Outcomes of Curative Intent Radiotherapy by Helical Tomotherapy for Laryngeal Squamous Cell Carcinoma: A Retrospective Analysis in a Tertiary Referral Center | Abstract HTML PDF |
Atsuto Katano, Hideomi Yamashita | 136-142 |
doi: https://doi.org/10.14740/wjon1638 |
Case Report
Significance of Beta Human Chorionic Gonadotropin in Predicting Disease Progression in Uterine Leiomyosarcoma | Abstract HTML PDF |
Abdulla Alzibdeh, Issa Mohamad, Maysa Al-Hussaini, Samer Salah, Abdalgani Jaradat, Ramiz Abuhijlih, Fawzi Abuhijla | 143-148 |
doi: https://doi.org/10.14740/wjon1748 |