Editor-in-Chief ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope |
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- Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis
Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.
Read More >> - Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis
The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.
Read More >> - Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment
The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.
Read More >> - Fluctuations in Gut Microbiome Composition During Immune Checkpoint Inhibitor Therapy
Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1 (PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in outcomes of non-small cell lung cancer (NSCLC).
Read More >> - Improving Gastrointestinal Cancer Care by Enhanced Recovery Protocol Implementation
Enhanced recovery protocols (ERPs) have become the standard of care for patients undergoing elective small bowel surgeries but have not yet been adequately studied in community hospitals. In this study, a multidisciplinary ERP was developed and implemented at a community hospital to include minimal anesthesia, early ambulation and enteral alimentation, and multimodal analgesia.
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Trends of Oncological Quality of Robotic Gastrectomy for Gastric Cancer in the United States | | |||
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![]() Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases |
Current Issue |
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Vol. 14, No. 6, Dec 2023
Table of Contents
Review
Malignant Transformation of Long-Standing Ileal Crohn’s Disease Likely Favors Signet Ring Cell Adenocarcinoma Histology | Abstract HTML PDF Suppl1 Suppl2 |
Matthew G.K. Benesch![]() ![]() ![]() |
447-456 |
doi: https://doi.org/10.14740/wjon1605 |
Original Article
The Role of Crohn Disease on Breast Cancer Incidence: A Clinical Analysis | Abstract HTML PDF |
Raina K. Patel, Lexi Frankel, Matthew Cardeiro, Wade Hansen, Kazuaki Takabe, Omar M. Rashid | 457-463 |
doi: https://doi.org/10.14740/wjon1644 |
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis | Abstract HTML PDF |
Rui Wang, Shu Ling Liu, Shu Ling Liu, Quan Quan Guo, Shu Ling Liu, Xiao Hong Shi, Mei Mei Ma | 464-475 |
doi: https://doi.org/10.14740/wjon1681 |
Construction and Validation of a Novel Nomogram for Predicting the Risk of Metastasis in a Luminal B Type Invasive Ductal Carcinoma Population | Abstract HTML PDF |
Xu Dong Zhu, Jia Hui Yu, Fu Lu Ai, Yue Wang, Wu Lv, Gui Lin Yu, Xian Kui Cao, Jie Lin | 476-487 |
doi: https://doi.org/10.14740/wjon1553 |
Prevalence and Prognosis of Secondary Genetic Aberrations Among Patients With Core Binding Factor Acute Myeloid Leukemia: A Mitelman Database Analysis | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 |
Renzo Martin Chapilliquen Ramirez![]() ![]() ![]() |
488-498 |
doi: https://doi.org/10.14740/wjon1661 |
Efficiency of the Robotic Platform in Improving the Rate of Sphincter Preservation in Patients With Mid and Low Rectal Cancer | Abstract HTML PDF |
Thalia Petropoulou, Kassiani Theodoraki, Panagiota Kitsanta, Shwan Amin | 499-504 |
doi: https://doi.org/10.14740/wjon1581 |
Development and Validation of Nomograms Based on Nutritional Risk Index for Predicting Extracapsular Extension and Seminal Vesicle Invasion in Patients Undergoing Radical Prostatectomy | Abstract HTML PDF |
Ze Nan Liu, Zi Ang Li, Ji De He, Jia Long Wu, Lei Qiu, Zhen Kun Zhao, Min Lu, Hai Bi, Jian Lu | 505-517 |
doi: https://doi.org/10.14740/wjon1718 |
Addition of Olaparib to the New Hormonal Agent Regimen for Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis | Abstract HTML PDF |
Syah Mirsya Warli![]() ![]() ![]() ![]() |
518-528 |
doi: https://doi.org/10.14740/wjon1685 |
Efficacy of First-Line Immunotherapy Combined With Chemotherapy in Extensive-Stage Small Cell Lung Cancer Patients With Different Brain Metastases Status: A Systematic Review and Meta-Analysis | Abstract HTML PDF |
Wen Hua Zhao, Shou Feng Wang, Cui Yun Su, Xin Bin Pan | 529-539 |
doi: https://doi.org/10.14740/wjon1726 |
Vasopressin Analog [V4Q5]dDAVP Exerts Cooperative Anticancer Effects in Combination With Low-Dose 5-Fluorouracil on Aggressive Colorectal Cancer Models | Abstract HTML PDF Suppl1 Suppl2 Suppl3 |
Natasha T. Sobol, Luisina M. Solerno, Candela Llavona, Daniel F. Alonso![]() ![]() |
540-550 |
doi: https://doi.org/10.14740/wjon1715 |
Clinicopathological Characteristics and Prognosis of Triple-Negative Apocrine Carcinoma: A Case-Control Study | Abstract HTML PDF |
Chiho Suzuki, Akimitsu Yamada, Kei Kawashima, Mahato Sasamoto, Yoshie Fujiwara, Shoko Adachi, Masanori Oshi, Tomoko Wada, Shinya Yamamoto, Kazuhiro Shimada, Ikuko Ota, Kazutaka Narui, Sadatoshi Sugae, Daisuke Shimizu, Mikiko Tanabe, Takashi Chishima, Yasushi Ichikawa, Takashi Ishikawa, Itaru Endo | 551-557 |
doi: https://doi.org/10.14740/wjon1694 |
Genetically Predicted Causal Effects of Gut Microbiota and Gut Metabolites on Digestive Tract Cancer: A Two-Sample Mendelian Randomization Analysis | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 Suppl8 Suppl9 Suppl10 Suppl11 Suppl12 Suppl13 Suppl14 Suppl15 |
Xu Jia Li, Meng Ge Gao, Xu Xian Chen, Yu Ming Rong, Ling Li Huang![]() |
558-569 |
doi: https://doi.org/10.14740/wjon1737 |
Case Report
Catch the Calcium: T-Cell Histiocyte-Rich B-Cell Lymphoma Presenting as Hypercalcemia | Abstract HTML PDF |
Richard K. Okeke, Gabriella A. Harmon, Ijeoma G. Okeke, Jake W. Schuler, Sahana J. Sangappa, Jonathan S. Harmon, Evgeniya Angelova, Xiu Sun, Angelo A. Chinnici | 570-574 |
doi: https://doi.org/10.14740/wjon1610 |
Dramatic Improvement of Pulmonary Tumor Thrombotic Microangiopathy in a Breast Cancer Patient Treated With Bevacizumab | Abstract HTML PDF |
Aki Kimura, Akimitsu Yamada, Masanori Oshi, Mina Nakayama, Naohiro Komura, Teruyasu Sugano, Shinya Yamamoto, Kazutaka Narui, Itaru Endo | 575-579 |
doi: https://doi.org/10.14740/wjon1691 |
Osteoblastic Bone Reaction Developing During Treatment With Sintilimab and Bevacizumab in a Patient With KRASG12V-Mutant Lung Adenocarcinoma | Abstract HTML PDF |
Chang Jun Chen![]() |
580-583 |
doi: https://doi.org/10.14740/wjon1702 |
Borderline Phyllodes Tumor in a Child | Abstract HTML PDF |
Esperanza Millan-Arreola![]() ![]() |
584-588 |
doi: https://doi.org/10.14740/wjon1716 |