World Journal of Oncology

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Editor-in-Chief
Kazuaki Takabe, MD, PhD, FACS
Professor, Alfiero Foundation Chair, and Clinical Chief of Breast Surgery in Department of Surgical Oncology at Roswell Park Comprehensive Cancer Center in Buffalo, New York, USA
Professor of Surgery with Tenure in Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, the State University of New York, USA
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ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope

Indexed and covered: PubMed, PubMed Central, Scopus, Elsevier Embase, Web of Science, Chemical Abstract (CA), EBSCO, Worldcat, Google, Google Scholar.

JCR Impact Factor (JIF 2023): 2.1
CiteScore (2023): 6.1; Journal Rank: 126/404 (Oncology)


Journal archiving and digital preservation:
Portico


Highlights

  • DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression

    DNA damage-induced apoptosis suppressor (DDIAS) has recently been discovered to induce cancer progression, but its functions and mechanisms in glioma have not been well studied. In this study, DDIAS expression in glioma tissues was analyzed by the Gene Expression Profiling Interactive Analysis server (GEPIA) and the Gene Expression database of Normal and Tumor tissue 2 (GENT2) databases.

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  • Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells

    The dynamic changes between glycolysis and oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) output, along with glucose, glutamine, and fatty acid utilization, etc., lead to the maintenance and selection of growth advantageous to tumor cell subgroups in an environment of iron starvation and hypoxia.

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  • Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis

    Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.

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  • Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis

    The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.

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  • Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment

    The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.

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Featured

 

 

Featured

 

Pigs: Large Animal Preclinical Cancer Models
Pigs are playing an increasingly vital role as translational biomedical models for studying human pathophysiology. The annotation of the pig genome was a huge step forward in translatability of pigs as a biomedical model for various human diseases. Full Text

Sphingosine-1-Phosphate Inhibition Increases Endoplasmic Reticulum Stress to Enhance Oxaliplatin Sensitivity in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer resistant to current therapies, including oxaliplatin (Oxa). Growing evidence supports the ability of cancers to harness sphingolipid metabolism for survival. Full Text


Key Clinical Image

Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. Full Text


Current Issue

 


Vol. 15, No. 5, Oct 2024

Table of Contents

Review

Cryotherapy in the Treatment of Early-Stage Breast Cancer Abstract HTML PDF
Chelsey C. Ciambella, Kazuaki Takabe 737-743
doi: https://doi.org/10.14740/wjon1909

Original Article

Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7
Harinarayanan Janakiraman, Zachary Gao, Yun Zhu, Jiangling Dong, Scott A. Becker, Alhaji Janneh, Besim Ogretmen, E. Ramsay Camp 744-757
doi: https://doi.org/10.14740/wjon1890
On the Origin of Abdominal Venous Leiomyosarcomas: The Role of the Sex-Hormone Drainage Pathways Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5
Usman Tarique, David P. Cyr, Carlo Morosi, Brendan C. Dickson, Giorgio Greco, Carol J. Swallow, Dario Callegaro, Rebecca A. Gladdy, Korosh Khalili 758-768
doi: https://doi.org/10.14740/wjon1884
Prognostic Implications of Timing of Immunotherapy in Stage IV Non-Small Cell Lung Cancer Abstract HTML PDF Suppl1 Suppl2
Jorge Raul Vazquez-Urrutia, Max Greenberg, Junjia Zhu, Shinkichi Takamori, Takefumi Komiya 769-776
doi: https://doi.org/10.14740/wjon1924
Multi-Gene Panel Testing for Hereditary Cancer Predisposition Among Patients Sixty-Five Years and Above Diagnosed With Breast Cancer Abstract HTML PDF Suppl1 Suppl2
Hikmat Abdel-Razeq, Faris Tamimi, Baha Sharaf, Sarah M. Nielsen, Brandie Heald, Kathryn E. Hatchell, Edward D. Esplin, Hira Bani Hani, Khansa Al-Azzam, Mais Alkyam, Rawan Mustafa, Areej Al-Atary 777-783
doi: https://doi.org/10.14740/wjon1919
Assessment of Five-Year Relative Survival of Patients With Endometrial Cancer: A Period Analysis Abstract HTML PDF
Xiao Jiao Zhao, Xin Bing, Qi Qi Lei, Yong Ran Cheng, Jun Yang, Liang You Wang, Tian Hua Chen, Tian Hui Chen 784-791
doi: https://doi.org/10.14740/wjon1921
Analysis of Pancreatic Cancer Genetic Risk Factors in a Multi-Ethnic Population Sample Abstract HTML PDF Suppl1
Abdullah Al-Qahtani, Ali Al-Ali, Bency John, Kusum Kapila, Rabeah Al-Temaimi 792-800
doi: https://doi.org/10.14740/wjon1911
Patterns and Frequency of Pathogenic Germline Variants Among Prostate Cancer Patients Utilizing Multi-Gene Panel Genetic Testing Abstract HTML PDF Suppl1 Suppl2
Ramiz Abu Hijlih, Baha Sharaf, Samer Salah, Hira Bani Hani, Sarah M. Nielsen, Brandie Heald, Edward D. Esplin, Rami Ghanem, Abdulla Alzibdeh, Tamer Al-Batsh, Yosra Al-Masri, Hikmat Abdel-Razeq 801-808
doi: https://doi.org/10.14740/wjon1896
SNX4 Is Correlated With Immune Infiltration and Prognosis in Clear Cell Renal Cell Carcinoma Abstract HTML PDF Suppl1
Yu Meng Chai, Zhong Bao Zhou, Run Ze Liu, Yuan Shan Cui, Yong Zhang 809-824
doi: https://doi.org/10.14740/wjon1868
Simultaneous Determination of Methotrexate Concentrations in Human Plasma and Cerebrospinal Fluid Using Two-Dimensional Liquid Chromatography: Applications in Primary Central Nervous System Lymphoma Abstract HTML PDF
Yan Hong Wang, Qiang He, Feng Wang, Hao Jiang, Jing Shi, Ji Ma, Yu Guo Liu 825-836
doi: https://doi.org/10.14740/wjon1910

Case Report

An Extremely Rare Case of Primary Malignant Melanoma of the Kidney Abstract HTML PDF
Akane Onogi, Daichi Kodama, Naoki Watanabe, Takashi Ishida, Hisao Komeda, Shuji Mikami, Takuji Tanaka 837-843
doi: https://doi.org/10.14740/wjon1899
Secondary Hemophagocytic Lymphohistiocytosis Following Dostarlimab Treatment in a Patient With Metastatic Endometrial Cancer Abstract HTML PDF
Emilie Rollet, Sebastien Puigrenier, Abeer Najem, Benoit Desgrousilliers, Pierre Riviere 844-850
doi: https://doi.org/10.14740/wjon1917

Erratum

Correction to: Empowerment-Led Guided Self-Help Intervention for Symptom Burden in Breast Cancer Women Treated With Ovarian Function Suppression: A Randomized Trial Protocol Abstract HTML PDF
Yuan Li, Yun Yun Chen, Su Xing Wang, Zheng Yue Dai, Jia Song Cui, Yu Fei Xing, Qing Wu, Qiong Fang 851
https://doi.org/10.14740/wjon1817c
 

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World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.                     
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