Breast Metastasis From Castrate-Resistant Prostatic Adenocarcinoma Mimicking as a Second Primary: A Case Report

Valerie Lima, Felycette Gay Martinez-Lapus, Kenny Jun Demegillo

Abstract


The occurrence of breast metastasis from prostate carcinoma and primary breast carcinoma in men may cause a diagnostic dilemma. This report aims to present a patient diagnosed with metastatic castrate-resistant prostatic adenocarcinoma who developed breast metastasis mimicking as a second primary. A 57-year-old male patient presented with a breast mass while undergoing hormonal therapy for prostatic adenocarcinoma. The initial histopathologic diagnosis of the breast specimen was an infiltrating ductal breast carcinoma. The breast mass enlarged after four cycles of docetaxel. Immunostaining with prostate-specific antigen (PSA) and prostate-specific acid phosphatase (PSAP) was done on the breast specimen revealing a negative PSA and a moderately staining PSAP. These stains confirmed the diagnosis of a breast metastasis from prostatic adenocarcinoma. The differentiation between primary breast carcinoma and breast metastasis from prostate carcinoma is crucial. Hence, immunohistochemistry staining should be utilized for diagnosis and appropriate management.




World J Oncol. 2020;11(1):37-40
doi: https://doi.org/10.14740/wjon1258

Keywords


Breast metastasis; Prostate cancer; Castrate-resistant prostate cancer; Prostate-specific antigen; Prostate-specific acid phosphatase

Full Text: HTML PDF
 

Browse  Journals  

     

Journal of clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics

 

 

 

 

 

World Journal of Oncology, bimonthly, ISSN 1920-4531 (print), 1920-454X (online), published by Elmer Press Inc.            
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.wjon.org   editorial contact: editor@wjon.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.