Gliosarcoma in Young Adults: A Rare Variant of Glioblastoma

Neha Kakkar, Jaspreet Kaur, Gunjesh Kumar Singh, Pragya Singh, Fouzia Siraj, Ajay Gupta

Abstract


Gliosarcoma is a rare central nervous system (CNS) malignancy. It is characterized by classical biphasic histological pattern with both glial and sarcomatous components, often seen in fifth and sixth decade of life. They are generally located in the supratentorial region. Due to its rarity, exact treatment recommendations are not available in literature. Since it is considered as a variant of glioblastoma multiforme (GBM), it is treated with surgery followed by adjuvant radiotherapy and temozolomide-based chemotherapy. We present a series of four cases of this rare malignancy that were treated at our institute.




World J Oncol. 2017;8(2):53-57
doi: https://doi.org/10.14740/wjon998w


Keywords


Gliosarcoma; Surgery; Chemotherapy; Radiotherapy; Young adults; Outcome

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